LABOKLIN Service ID: 8697<\/span><\/p> Our cooperation partner Prof. Tosso Leeb and his team from the University of Bern have identified a new genetic variant causing a neurological disease called CNS atrophy and cerebellar ataxia (CACA) in the breed Belgian Shepherd. FLP<\/p><\/td><\/tr> Belgian Shepherd Dog, Groenendael, Laekenois, Malinois, Tervueren<\/p><\/td><\/tr> autosomal recessive<\/p><\/td><\/tr> 1 - 2 weeks after arrival of the sample in the lab<\/p><\/td><\/tr><\/table>\n","protected":false},"excerpt":{"rendered":" CNS atrophy with cerebellar ataxia (CACA)LABOKLIN Service ID: 8697Our cooperation partner Prof. Tosso Leeb and his team from the University of Bern have identified a new genetic variant causing a neurological disease called CNS atrophy and cerebellar ataxia (CACA) in the breed Belgian Shepherd. Affected puppies show uncoordinated movements, intention tremor, short episodes of spastic…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":1419950,"menu_order":178,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_seopress_robots_primary_cat":"","_seopress_titles_title":"","_seopress_titles_desc":"","_seopress_robots_index":"","footnotes":""},"class_list":["post-1433596","page","type-page","status-publish","hentry","description-off"],"_links":{"self":[{"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/pages\/1433596","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/comments?post=1433596"}],"version-history":[{"count":0,"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/pages\/1433596\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/pages\/1419950"}],"wp:attachment":[{"href":"https:\/\/laboklin.com\/ch-fr\/wp-json\/wp\/v2\/media?parent=1433596"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
\nAffected puppies show uncoordinated movements, intention tremor, short episodes of spastic fits, general elevated muscle tone and a reduced swallowing reflex. Moreover, affected puppies show less body weight increase as their unaffected littermates. First signs could be observed at the age of about 2 weeks. However, the severity of the signs are highly variable.
\nMany affected puppies have to be euthanized a few weeks after the first signs whereas an affected dog with less intense symptoms has been reported to become up to 10 years old.<\/p>Method<\/strong><\/td> Breed list<\/strong><\/td> Heredity<\/strong><\/td> Duration<\/strong><\/td>